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Our partner pharmacies have served 100,000+ patients

$129/month

Compounded · GLP-1 Care for Women 40+

Semaglutide Injection

Our partner pharmacies have served 100,000+ patients

For weight gain that
feels different after 40.

See if I qualify

No charge today Takes about 3 minutes

  • Board-certified physicians
  • State-licensed pharmacies
  • Same-day prescriptions
  • 2-day shipping
Compounded semaglutide injection — Cypress Health
  • 2-day shipping · direct-to-door
  • Cancel anytime before your next ship date
  • Includes clinician oversight, dose escalation, and side-effect support
Your care
U.S.-LicensedPhysicians
State-LicensedCompounding Pharmacies
HIPAACompliant
Available inAll 50 US states

Pricing

Your monthly plan.

One simple monthly subscription. Cancel anytime before your next ship date.

Why semaglutide

A first step most women tolerate well.

Compounded semaglutide injection for weight loss

The active ingredient — semaglutide — has been studied extensively for weight management. The dose ramp is gentle, the side-effect profile is well understood, and most women find compounded semaglutide tolerable from the start.

For women in midlife, semaglutide is often the first GLP-1 we recommend. If response plateaus or doesn't reach goals, your clinician can talk through whether tirzepatide or a different protocol might fit better.

Whether semaglutide is right for you depends on your medical history, current medications, and goals. Your clinician will determine that. The intake is the first step.

Dosing

A measured start. Adjusted as you go.

1
Weeks 1–4 · Starting dose
0.25 mg once weekly. The starting dose is intentionally low to let your body adjust; mild GI symptoms are common in the first week or two and typically settle.
2
Weeks 5+ · Dose escalation
Your clinician adjusts your dose — typically 0.5 mg, 1.0 mg, 1.7 mg, 2.4 mg over time, based on response, tolerance, and goals.
3
Ongoing · Care, not just refills
Your plan includes ongoing clinician oversight, dose adjustment, side-effect support, and lab review when needed.

Side effects & safety

What to know before you start.

Woman reviewing health information at home

Most common: nausea, decreased appetite, mild diarrhea, constipation, fatigue. Typically dose-related and most pronounced in the first week of each new dose.

Less common but important: pancreatitis, gallbladder issues, low blood sugar (especially if you also take insulin or sulfonylureas). Tell your clinician about all current medications.

Muscle mass during treatment: GLP-1 therapy can be associated with loss of lean mass, particularly in women in midlife. Your clinician will discuss strategies to protect muscle — typically resistance training and adequate dietary protein — as part of your care plan.

Not appropriate if: you have a personal or family history of medullary thyroid carcinoma or MEN2; you're pregnant, planning pregnancy, or breastfeeding; or you have severe GI disease or end-stage organ disease.

Questions

Answers to
common questions.

How is compounded semaglutide prepared?
Compounded by a licensed 503A pharmacy on a per-patient basis.
Compounded semaglutide is prepared by a state-licensed U.S. pharmacy operating under Section 503A of the Federal Food, Drug, and Cosmetic Act. Each preparation is dispensed per-patient based on a licensed clinician's prescription. Compounded preparations are not interchangeable with branded medications and may differ in formulation, strength, and clinical profile. Your clinician will help determine whether compounded semaglutide is appropriate for your specific health profile.
What should I expect after starting?
Everyone responds differently — your clinician tracks how you respond over time.
Everyone responds differently. Your clinician monitors how your body responds over time and adjusts your plan accordingly. Whether and how you respond depends on your individual health, and your clinician will review your progress with you. The largest published trial of injectable semaglutide for weight management — STEP 1 (Wilding et al., NEJM 2021) — showed an average ~14.9% body weight loss over 68 weeks at the 2.4 mg weekly dose. Outcomes from clinical trials of branded products cannot be directly attributed to compounded preparations. Your individual response depends on dose, time, lifestyle, and biology.
When am I charged?
Not until a clinician confirms your eligibility — typically within 24–48 hours.
You're not charged when you submit your assessment. Your card is securely saved while a licensed clinician reviews your case, typically within 24 to 48 hours. If you're approved, you'll receive an email confirmation before any charge is processed. If you're not approved, you're not charged at all.
Will I need to stay on treatment after I reach my goal?
Most people regain weight without a structured maintenance plan. We plan that step with you, not around you.
This is one of the most important conversations you'll have with your clinician. The available evidence — including the STEP 4 withdrawal trial (Rubino et al., JAMA 2021) — shows that most people regain weight when they stop GLP-1 therapy without a structured maintenance plan. Some women step down to a lower maintenance dose; some wean off with continued resistance training and protein-forward eating to preserve lean mass; some choose to continue at full dose. There's no single right answer, and the right path is decided with you.
Can I cancel?
Cancel anytime before your next ship date.
Your monthly subscription can be cancelled anytime before your next ship date — there's no long-term commitment. Medication, supplies, and shipping are all included while you're active.
Is insurance required?
No — transparent flat-rate pricing, no hidden fees.
No. Cypress offers transparent, flat-rate pricing without insurance and no hidden fees. Medication, supplies, and shipping are all included.
Can I use my FSA/HSA?
Yes — itemized receipts provided for self-submission.
Yes. HSA and FSA cards are accepted on any plan. We also provide itemized receipts in case you need to self-submit to your benefits provider.

See if semaglutide is right for you.

The 3-minute medical screener is free. If you're a candidate, your clinician typically follows up within 24 hours.

See if I qualify
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